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Leukeran ( Chlorambucil)
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Leukeran, also known as Chlorambucil, is useful in the treatment of certain cancers.
Drug Uses

Leukeran is useful in the treatment of certain cancers. It may also be used for certain other conditions as and when prescribed by your medical practitioner. Being an alkylating agent it binds to the RNA or DNA of some of the cancer cells. This in turn helps in slowing down their growth as well as reproduction.


Medication must always be taken as advised by your medical practitioner/physician. If you are unsure, then please contact your physician for precise instructions. On the other hand, the medicine label usually contains dosage instructions which also may be followed.

Do not take Leukeran if you have been suffering from vomiting or are feeling nauseated.

A full glass of water when taken with Leukeran always ensures better absorption.

Medications are prescribed according to a dosage schedule which must be completed in order to reap the benefits of the treatment. Lapsed schedules render Leukeran ineffective. So, never stop in between unless advised by your physician.

One of the best ways to ensure that you do not miss out on a dose is to maintain a fixed regime for consuming Leukeran each day.

Drug Class and Mechanism

Chlorambucil, also known as alkylating agents, belongs to the group of drugs which are commonly referred to as cancer drugs, antineoplastics, chemotherapy, or "chemo". They are useful in treating various types of cancers in order to slow or even stop the growth of cancer cells. A combination of various types of cancer drugs are often used to achieve better results and also to minimize side effects.

Missed Dose

You must maintain a schedule for taking the medicine at the same time each day so that you do not miss out on any doses. But, in the advent of a missed dose, take it as soon as you remember so that you can compensate for the loss of the dose.

But, then you may need to adjust your remaining doses accordingly. And if it is almost time for the next dose, then please skip the missed dose and continue with the normal schedule.

Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects.


Leukeran must be stored at a cool and dark place that prevents it from direct exposure to sunlight. It should also be protected from kids and pets. You must store it in your refrigerator with 2 to 4 degrees C.

Leukeran can lead to cancer and can even seek to weaken your bone marrow. The blood cells in the bone marrow are mainly made to protect you against infections and illness. You must visit your doctor as soon as you develop the signs of infection. Leukeran can also cause damage in the chromosomes or genes and is known to have left men and women sterile and has even caused birth defects.

Ensure that your doctor is aware of your past and current medical history before you start any new treatment or medication. This must include any and all diseases that you have suffered /suffer from, all subscription and over the counter medication that you are taking, including vitamins and herbal supplements. This will help avoid a possible interaction or allergy.

You must not touch your eyes or even the inside of your nose without washing your hands. It is advisable to exercise caution with sharp objects like nail cutters and safety razors and also avoid activities like contact sports so as to lower the chance of getting bruised, cut, or injured. It is important to visit your doctor regularly. Even regular blood tests should be done so as to monitor the therapy.
Side Effects

It is common to experience some temporary and mildly annoying side effects as the body adjusts to the new drug. These rarely require any special medical attention and usually fade away automatically.

These include nausea, vomiting and even changes in menstrual period.

But, if they refuse to fade away or become bothersome, then seek medical attention immediately.

On the other hand, if you experience serious side effects like fever, chills, easy bleeding, painful or difficult urination, tarry stools, joint pain, blood in urine or stools, swelling in various parts of the body, small red spots on the skin, sores in mouth or on lips, cough, yellow eyes and skin, side pain, trouble in walking, stomach pain, muscle twitching, rash, agitation, confusion, itching, hallucinations, weakness, dizziness, paralysis and also trouble in breathing.

Seek immediate medical attention if you notice any of these side effects.

In some cases, you may also notice side effects that are not listed here. In such cases, seek medical attention.
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